Digestive Disease Center

Leading the world in digestive health through innovation and excellence.
M.U.S.C. Digestive Disease Center logoChanging What's Possible®

MUSC Digestive Disease Center

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Reception: 843-792-6999Scheduling: 843-792-6982Clinical Trials: 843-876-4303
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Patient Care

Our physicians and surgeons strive to provide you with the care and information you want.


Reaching out to the professional community, knowing that education is the key to better medicine.


A wide variety of clinical trials and research are the basis of our search for better G.I. solutions.



Gallstones and bile duct stones, which are both created in the gallbladder, form when substances in the bile create hard, crystal-like particles. They may be as small as a grain of sand, or as large as a golf ball.

Read about other G.I. diseases.

Anal Itching


Anal itching is a rash or irritation of the skin just outside of the anal opening. Usually raw and chapped, small ulcers or sores may also be present on the skin. This can cause severe itching, burning and even pain.



Endoscopic Retrograde Cholangio Pancreatography (ERCP) is a method for getting into the bile duct and pancreas though the mouth using a long, flexible, narrow tube with a camera at the end.

Read about other G.I. procedures.

MUSC Anchors Major Publication on Sphincter of Oddi Dysfunction

The sphincter of Oddi controls the flow of bile and pancreatic juices from the liver and pancreas into the duodenum. Dysfunction of the sphincter is often considered as a cause of biliary-type pain in patients who have previously undergone gall bladder removal. Dr. Peter Cotton and colleagues from seven expert centers in the USA undertook a trial in 214 patients in which the standard approach (ERCP with manometry and sphincterotomy) was compared with a sham procedure. Patients did not know what treatment they had received. Read more

Jennifer Seminerio, MDAssistant Professor of Medicine

portrait of Dr. Jennifer Seminerio
Dr. Jennifer Seminerio

Dr. Jennifer Seminerio completed her residency in Internal Medicine at the Mayo Clinic in Rochester, MN and fellowship in Gastroenterology and Hepatology at University of Pittsburgh Medical Center in Pittsburgh, PA. During fellowship training, she had a specific focus in Inflammatory Bowel Disease (IBD) having spent training in an outpatient IBD clinic, as well as inpatient IBD service.

Her clinical focus is in IBD with interest in obesity and its effect on the gastrointestinal tract. Research interests have focused on obesity and its effects on IBD as well as grant-funded research on obesity and GI hormones.

From a leadership perspective, Dr. Seminerio served as chief fellow at UPMC and plans on pursuing future rolls in this arena.View faculty list

Top of page

Why should I visit the Medical University of South Carolina?

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MUSC Ashley River Tower

Your doctor will probably agree with you about your preference to come to MUSC. We offer excellent patient care at a state-of-the-art facility, in a historic setting in the southeastern United States. Our doctors are nationally ranked among the highest in the nation. We employ a multidisciplinary approach to the treatment of patients using the latest technology in medicine.

Come see why MUSC is changing what's possible®.

Read more about why you should choose MUSC for your healthcare needs.